Young man in a market
Member Highlights

Member Highlight: Meet Kenta Yamamoto

I’m an MD/PhD student at the University of Pittsburgh Medical Scientist Training Program, in the laboratory of Dr. Sarah Gaffen, and I’m studying the functions of RNA-binding proteins in T cells mediating inflammatory disease. Previously, I studied spinal cord regeneration in the axolotl salamander with Dr Karen Echeverri and how [READ MORE]

Photo of Dominic Ritacco
New Member Mini-Bios

Dominic Ritacco, Columbia University Medical Center

Dominic Ritacco is a graduate student in the Gaudet lab at Columbia University’s Department of Microbiology and Immunology. Dominic received his B.S. in Biochemistry from the University of Wisconsin-Madison. He has previously conducted infectious disease research in the Moormann lab at the University of Massachusetts Chan Medical School and cell [READ MORE]

Banner Image of ICIS President, Sarah Gaffen
Featured Article!

Presidents Message: What the Cytokines Meeting Means to Me

If you only attend one conference this year… here’s why it should be Cytokines-2025! Just Right Ever since I attended my first Cytokines conference (Amsterdam, 2000), this meeting has been THE event on my scientific calendar. I admit to being a little biased, but I think Cytokines conferences are perfect [READ MORE]

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Member Highlights

Member Highlight: Meet Deanna Santer, Ph.D.

My lab is passionate about human interferons and especially type III interferons where there is still a lot to learn about! We are interested in how interferons regulate immune responses. However, when I’m not in the lab I like playing sports and hanging out with my family. Scientist should not [READ MORE]

Clinical Trials, contributed by Howard A. Young
Clinical Trials

Interferon Alfa Therapy Based on Th17 Profile in Membranous Nephropathy (ALPHAGEM)

ClinicalTrials.gov ID NCT05941845 Sponsor Centre Hospitalier Universitaire de Nice Information provided by Centre Hospitalier Universitaire de Nice (Responsible Party) Study Overview – Brief Summary Membranous Nephropathy (MN) is a renal autoimmune disease mediated by autoantibodies. Current management is based on the use of immunosuppressive therapies. MN patients with a pro-inflammatory Th17 [READ MORE]

Clinical Trials, contributed by Howard A. Young
Clinical Trials

Pegylated Interferon α-2b in Combination With Ruxolitinib for Treating Hydroxyurea-resistant/Intolerant PV (PV)

ClinicalTrials.gov ID NCT05870475 Sponsor Institute of Hematology & Blood Diseases Hospital, China Information provided by Institute of Hematology & Blood Diseases Hospital, China (Responsible Party) Study Overview – Brief Summary Study purpose: To compare the efficacy and safety of pegylated interferon α-2b in combination with ruxolitinib versus pegylated interferon α-2b alone [READ MORE]

Clinical Trials, contributed by Howard A. Young
Clinical Trials

Human Recombinant Interferon Gamma in the Treatment of Ventilator-acquired Pneumonia in ICU Patients (IGNORANT)

ClinicalTrials.gov ID NCT05843786 Sponsor Hospices Civils de Lyon Information provided by Hospices Civils de Lyon (Responsible Party) Study Overview – Brief Summary Clinical presentation of patients after severe injury such as a severe infection, trauma or extensive burns is characterized by the simultaneous occurrence of dysregulation of the initial inflammatory response [READ MORE]

Casual photos of Kristin Patrick
Member Highlights

Member Highlight: Meet Kristin Patrick, Ph.D.

As an RNA biologist-turned-immunologist, my lab studies the role of RNA processing in macrophage activation and antibacterial immunity. My lab is a vibrant, supportive and collaborative space that values diversity, creativity, and hard work. My name is Kristin Patrick, Ph.D. I am currently an Associate Professor in the Department of [READ MORE]

Scientific charts and graphs
Special Article of Interest

“Transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection” published in the Journal of Experimental Medicine

The following interview was conducted by Signals+ Editor Di Yu, Ph.D. The Journal of Experimental Medicine (JEM) recently published the study by Benjamin J. Broomfield et. al. showing early, short-term inhibition of IFN-I optimizes TSCM cell differentiation. Broomfield is a Ph.D. candidate in the Joanna Groom lab at WEHI. Highlights of [READ MORE]

Joaquin Espinosa enjoying a hike in the woods
Member Highlights

Member Highlight: Meet Joaquin M. Espinosa, Ph.D.

My team investigates the impacts of interferon hyperactivity and immune dysregulation in Down syndrome. We are testing the hypothesis that immune dysregulation drives many of the clinical and developmental hallmarks of Down syndrome. There is now a vibrant community of immunologists studying Down syndrome, and I believe that attending the [READ MORE]