Reviews of Interest

The Fc Key to Understanding Anti-TIGIT Biology

In the Phase 2 CITYSCAPE trial, Tiragolumab, an anti-TIGIT antibody, demonstrated efficacy when combined with Atezolizumab, an anti-PD-L1, compared to Atezolizumab alone for the treatment of non-small cell lung carcinoma. In mouse models, inhibition of both the TIGIT and PD-1 pathways was shown to synergistically function to reinvigorate T cell [READ MORE]

Reviews of Interest

Reviews of Interest

April 17, 2024 – Reviews of Interest PMID: 37726402 Anti-cytokine autoantibodies: mechanistic insights and disease associations. Cheng A, Holland SM. Nat Rev Immunol. 2024 Mar;24(3):161-177. doi: 10.1038/s41577-023-00933-2. Epub 2023 Sep 19.PMID: 37726402 Review. This review provides a comprehensive overview of the emerging field of anti-cytokine autoantibodies (ACAA), including their pathological [READ MORE]

Reviews of Interest

COVID-19 special collection

COVID-19 special: PMID: 36198912 COVID-19 and cellular senescence. Schmitt CA, Tchkonia T, Niedernhofer LJ, Robbins PD, Kirkland JL, Lee S. Nat Rev Immunol. 2022 Oct 5:1-13. doi: 10.1038/s41577-022-00785-2. Online ahead of print.PMID: 36198912 Free PMC article. Review.   PMID: 36631691 Innate immune evasion strategies of SARS-CoV-2. Minkoff JM, tenOever B. Nat Rev Microbiol. [READ MORE]

COVID-19 Special

COVID-19 Special

COVID-19 special: PMID: 36198912 COVID-19 and cellular senescence. Schmitt CA, Tchkonia T, Niedernhofer LJ, Robbins PD, Kirkland JL, Lee S. Nat Rev Immunol. 2022 Oct 5:1-13. doi: 10.1038/s41577-022-00785-2. Online ahead of print.PMID: 36198912 Free PMC article. Review. PMID: 36631691 Innate immune evasion strategies of SARS-CoV-2. Minkoff JM, tenOever B. Nat Rev Microbiol. 2023 [READ MORE]