My research focuses on understanding how cytokine signaling, particularly IL-6, influences disease progression and drug resistance. I’m in the process of setting up my lab at Kuwait University, where aim to study the differences between classical and trans-signaling pathways of IL-6, and how they activate cells in distinct ways. Ultimately, my goal is to translate these insights into practical strategies for therapeutic development.
Please tell us your name, degree, where you currently work, and position.
My name is Amenah Alrabeea. I hold a PhD in Molecular Pharmacology, with both my undergraduate and master’s degrees in Molecular Biology. I currently work as an Assistant Professor in the Department of Pharmacology and Toxicology at the Faculty of Medicine, Kuwait University.
Where did you do your training?
I completed my undergraduate and master’s training in Molecular Biology at Kuwait University. I then pursued my PhD in Molecular Pharmacology at the University of Manchester, UK.
Briefly, what is your research about?
I’m in the process of establishing my lab, where I focus on studying IL-6 and its signaling pathways. I’m particularly interested in how IL-6 can have both pro- and anti-inflammatory effects, and what drives these differences during disease progression. Currently, my research explores how cytokines like IL-6 and IL-1β influence the function and expression of ATP-binding cassette (ABC) transporters, which play a key role in drug resistance and cell regulation.
Tell us your thoughts about ICIS: how has being involved in the Cytokine Society helped your career?
A well-organized conference can truly energize your research, whether it’s seeing leading scientists present their big-picture work or connecting with enthusiastic early-career researchers working in areas close to your own. It honestly feels like meeting the “science celebrities” whose papers you’ve been reading for years! Conferences like those organized by ICIS not only offer high-quality science but also open the door to valuable discussions, networking, and future collaborations.
Are there any particular friendships or collaborations that came specifically out of Cytokines meetings?
I’ve only attended the Cytokines meeting once so far, but it was a great opportunity to meet many inspiring scientists in the field. While no formal collaborations have come from it yet, I’m definitely looking forward to future meetings, not only to reconnect with those researchers but also to see how their work has progressed and possibly explore opportunities to collaborate down the line.
What Cytokines meeting(s) have been your favorites? Tell us about any special memories or anecdotes.
One highlight from the Cytokines meeting in South Korea (KAI2024) was attending Prof. Dr. Stefan Rose-John’s award lecture on IL-6. Having previously connected with him via email, it was a great opportunity to meet him in person and briefly exchange thoughts.
What do you like to do when not in the lab?
I love exploring new places, whether it’s traveling to a new country or just discovering a hidden spot nearby. And I always have my camera ready to capture the moment!
What is the best life/career advice you’ve ever received?
A valuable piece of advice that has stuck with me came from my master’s supervisor, Prof. Yunus Luqmani: “We are observing biology, not creating it, so don’t be discouraged by a negative result.” It’s a reminder I always keep in mind, especially on challenging lab days!
What book or TV show are you reading/watching right now that you recommend?
I really enjoyed reading The Inflamed Mind by Edward Bullmore and The Beautiful Cure by Daniel Davis. And as a fan of cooking shows, I’d also recommend The Final Table it’s a great mix of culinary competition and global flavors!
What is your favorite cytokine?
I think I’ve already given a hint, but of course, without hesitation, IL-6 is my favorite cytokine!
Follow Amena on Twitter/X: @AAlrabeea93