Immunology Group in a lab
Special Article of Interest

Challenges and Opportunities of Conducting High-Quality Research in Cytokine Biology and Immunology in Low- and Middle-Income Countries

The following perspective is by ICIS Member, Javier Mora, Ph.D., University of Costa Rica, Faculty of Microbiology. We welcome your comments and feedback, either to Prof. Mora (javierfrancisco.mora @ ucr.ac.cr) directly or to the ICIS Managing Director, Stephanie Flores (sflores @ cytokinesociety.org). Research in cytokines and immunology plays a pivotal [READ MORE]

Prof Kim Good-Jacobson
Member Highlights

Member Highlight: Meet Kim Good-Jacobson, PhD

The following interview was conducted by Signals+ Editor Maialen Sebastian-delaCruz, Ph.D. Connect with her on LinkedIn. My lab in Australia works on understanding how humoral memory is formed, and how this goes awry in chronic infection. I’m excited to be able to learn and make new collaborations from joining the Cytokine Society, so [READ MORE]

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Clinical Trials

Recombinant Interleukin-15

Recombinant Interleukin-15 in Combination With Checkpoint Inhibitors Nivolumab and Ipilimumab in People With Refractory Cancers ClinicalTrials.gov ID NCT03388632 Sponsor National Cancer Institute (NCI) Information provided by National Institutes of Health Clinical Center (CC) (National Cancer Institute (NCI)) (Responsible Party)

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Clinical Trials

Role of IL-5R Signaling

Role of IL-5R Signaling in Non-eosinophil Upper Airway Cells in CRSwNP (RECAP-5) ClinicalTrials.gov ID NCT05672030 Sponsor Brigham and Women’s Hospital Information provided by Tanya Laidlaw, MD, Brigham and Women’s Hospital (Responsible Party)

Yanick Crow in the lab
Member Highlights

Member Highlight: Meet Yanick Crow, M.D., Ph.D.

The following interview was conducted by Signals+ Editor Maialen Sebastian-delaCruz, Ph.D. Connect with her on LinkedIn. The best life/career advice I have ever received was, “The harder you work, the luckier you get.” In the Crow Lab, we are interested in human monogenic diseases associated with chronically enhanced production of type I interferons [READ MORE]

Headshots of Chris Hunter and Warren Leonard
Members in the News

Past-Presidents Dr Christopher A Hunter and Dr Warren J Leonard named AAI Distinguished Fellows

Congratulations Chris Hunter and Warren Leonard! Dr Christopher A Hunter and Dr Warren J Leonard were selected as Distinguished Fellows of the American Association of Immunologists (AAI) in this year’s class. Dr Hunter and Dr Leonard are Past-Presidents of International Cytokine and Interferon Society (ICIS) and of the International Cytokine [READ MORE]

Graphical abstract and citation of recent article from lab of Dr. Edward Chuong
Special Article of Interest

“Regulation of human interferon signaling by transposon exonization” published in Cell

The following interview was conducted by Signals+ Editor Maialen Sebastian-delaCruz, Ph.D. Connect with her on LinkedIn. A recent study by Pasquesi et al from the Chuong lab published in Cell, “Regulation of human interferon signaling by transposon exonization” showed that transposable element exonization can yield functional protein isoforms as seen for [READ MORE]

Elias A. Said, Ph.D., Associate Professor, Sultan Qaboos University, Muscat, Oman
Member Highlights

Member Highlight: Meet Elias Said

The following interview was conducted by Signals+ Editor Maialen Sebastian-delaCruz, Ph.D. Connect with her on LinkedIn. I am a researcher in the Immunology field, specifically innate immunity and cytokines. Also, an Associate Editor for scientific journals. My research has led to significant achievements, such as identifying the role of PD-1 in [READ MORE]

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Clinical Trials

Single-arm, Dose-escalation Trial of Long-acting Recombinant Human IL-7 (NT-I7, Efineptakin Alfa) for Idiopathic CD4 Lymphopenia

ClinicalTrials.gov ID NCT05600920 Sponsor National Institute of Allergy and Infectious Diseases (NIAID) Information provided by National Institutes of Health Clinical Center (CC) (National Institute of Allergy and Infectious Diseases (NIAID)) Study Overview Brief Summary Background: Idiopathic CD4 lymphopenia (ICL) is a syndrome characterized by low levels of certain immune cells [READ MORE]