Articles by Stephanie Flores

Clinical Trials, contributed by Howard A. Young
Clinical Trials

Pegylated Interferon α-2b in Combination With Ruxolitinib for Treating Hydroxyurea-resistant/Intolerant PV (PV)

May 4, 2025

ClinicalTrials.gov ID NCT05870475 Sponsor Institute of Hematology & Blood Diseases Hospital, China Information provided by Institute of Hematology & Blood Diseases Hospital, China (Responsible Party) Study Overview – Brief Summary Study purpose: To compare the efficacy and safety of pegylated interferon α-2b in combination with ruxolitinib versus pegylated interferon α-2b alone [READ MORE]

Clinical Trials, contributed by Howard A. Young
Clinical Trials

Human Recombinant Interferon Gamma in the Treatment of Ventilator-acquired Pneumonia in ICU Patients (IGNORANT)

May 4, 2025

ClinicalTrials.gov ID NCT05843786 Sponsor Hospices Civils de Lyon Information provided by Hospices Civils de Lyon (Responsible Party) Study Overview – Brief Summary Clinical presentation of patients after severe injury such as a severe infection, trauma or extensive burns is characterized by the simultaneous occurrence of dysregulation of the initial inflammatory response [READ MORE]

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Member Highlights

Member Highlight: Meet Kristin Patrick, Ph.D.

April 14, 2025

As an RNA biologist-turned-immunologist, my lab studies the role of RNA processing in macrophage activation and antibacterial immunity. My lab is a vibrant, supportive and collaborative space that values diversity, creativity, and hard work. My name is Kristin Patrick, Ph.D. I am currently an Associate Professor in the Department of [READ MORE]

Scientific charts and graphs
Special Article of Interest

“Transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection” published in the Journal of Experimental Medicine

April 14, 2025

The following interview was conducted by Signals+ Editor Di Yu, Ph.D. The Journal of Experimental Medicine (JEM) recently published the study by Benjamin J. Broomfield et. al. showing early, short-term inhibition of IFN-I optimizes TSCM cell differentiation. Broomfield is a Ph.D. candidate in the Joanna Groom lab at WEHI. Highlights of [READ MORE]

Joaquin Espinosa enjoying a hike in the woods
Member Highlights

Member Highlight: Meet Joaquin M. Espinosa, Ph.D.

March 31, 2025

My team investigates the impacts of interferon hyperactivity and immune dysregulation in Down syndrome. We are testing the hypothesis that immune dysregulation drives many of the clinical and developmental hallmarks of Down syndrome. There is now a vibrant community of immunologists studying Down syndrome, and I believe that attending the [READ MORE]

Headshot of Dr. Chen Yao
New Member Mini-Bios

New Member Mini-Bio: Chen Yao, Ph.D., University of Texas Southwestern Medical Center

March 31, 2025

Dr. Chen Yao is an assistant professor in the Department of Immunology at UT Southwestern Medical Center. Having earned her Ph.D. from the University of Minnesota under the guidance of Dr. Daniel Kaplan, Dr. Yao furthered her expertise through postdoctoral training in the systems immunology laboratory led by Dr. John [READ MORE]

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Clinical Trials

Early Interferon-beta Treatment for West-Nile Virus Infection

March 31, 2025

ClinicalTrials.gov ID NCT06510426 Sponsor Tel-Aviv Sourasky Medical Center Study Overview – Brief Summary West Nile virus (WNV) is a mosquito-borne virus which in majority of cases causes only self-limited disease. Despite that, in minority of cases (~0.5%) it can infect the brain and cause severe and even life-threatening disease (neuroinvasive disease). [READ MORE]

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Clinical Trials

Safety and Efficacy of Interferon-Gamma 1b in Patients with Candidemia

March 31, 2025

ClinicalTrials.gov ID NCT04979052 Sponsor Radboud University Medical Center Study Overview – Brief Summary A multi-center open label adaptive randomized interventional phase 2 study to evaluate safety and efficacy of rIFN-y treatment in patients with candidemia. Detailed Description A multi-center open label adaptive randomized interventional phase 2 study to evaluate safety [READ MORE]

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Clinical Trials

Interferon Alpha Therapy for Cervical CINI and HPV Infection

March 31, 2025

ClinicalTrials.gov ID NCT06137950 Sponsor Mongolian National University of Medical Sciences Study Overview – Brief Summary Mongolia is a traditionally nomadic and population is scarce in rural areas. Thus, the medical care service is not sufficient. In 2000, Mongolian government has developed and implemented the millennium project in cooperation with WHO. [READ MORE]

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Featured Article!

Shape the Future of ICIS: Run for a Leadership Position

March 17, 2025

The International Cytokines & Interferon Society (ICIS) thrives on the invaluable contributions of individuals who generously devote their time and expertise to the Society. As we look to the future, we invite you, our members, to consider stepping into leadership roles that will drive the field of cytokine and interferon research to new heights. [READ MORE]