Clinical Trials, contributed by Howard A. Young
Clinical Trials

Clinical Trials for the week of September 18

Interferon-α for TP53 Myeloid Malignancy Post Allo-HSCT | MITHRIDATE: Ruxolitinib Versus Hydroxycarbamide or Interferon as First Line Therapy in High Risk Polycythemia Vera (MITHRIDATE) | Effect of Low-dose Interferon-alfa2a on Peri-operative Immune Suppression (IPOS) [READ MORE]

Banner Image of ICIS President, Sarah Gaffen
Featured Article!

President’s Letter: Updates from your Cytokines Society

Congratulations to the newly-elected officers of the ICIS! Several are returning members, while others are joining the board for the first time. It is great to see so many people willing to give generously of their time and “sweat equity” (to adopt a turn of phrase from former ICIS President [READ MORE]

2024 Day of Immunology Participants
Featured Article!

Igniting High School Students’ Curiosity for Immunology

ICIS Council member, Carla Rothlin, Ph.D., recently interviewed Yale University’s Day of Immunology co-founders Dr. Lindsey Hughes, Sarah Ohashi and Sasha Tabachnikova. The following is a lightly edited summary of their conversation. What is Day of Immunology? Day of Immunology is an annual outreach event designed to introduce high school [READ MORE]

Carolina Lucas diving in Hawaii
Member Highlights

Member Highlight Interview: Meet Carolina Lucas, Ph.D.

My research focuses on the immune responses to emerging viral infections and vaccines in humans, with emphasis on older adults. The best advice I received was by the incredibly talented mentors I had and, in brief, it is to stay curious, celebrate wins no matter if they are big or [READ MORE]

Image of Howard Young titled: From Howard's Desk
From Howard's Desk

Bake your Lab Happy! And other thoughts from Editor Emeritus Howard Young

Howard Young has long been a proponent of employing treats to help maintain positive interactions among personnel in the laboratory. A Chocolate Peanut Butter Cake is an indulgent dessert that will promote the same level of harmony in the lab that is achieved in the rich chocolate and creamy peanut [READ MORE]

Graphic of Cytokines 2023 Attendee Testimonials
Annual Meeting

Something for Everyone: Don’t Miss Cytokines / KAI 2024

Lightening Talks and Networking Opportunities Cytokines 2024 and KAI 2024 is your unique opportunity to learn from global thought leaders in Cytokine and Interferon research and gain the insights, techniques, and experiences you need to build a vital network to amplify your impact. Event highlights include opportunities to: Meet senior [READ MORE]

Clinical Trials, contributed by Howard A. Young
Clinical Trials

Clinical Trials for the week of September 4

Pegylated Interferon Lambda for Treatment of COVID-19 Infection | Proportion of Clinical Improvement & Type 1 Interferon (IFN) Score Changes in Idiopathic Uveitis Patients With Interferon Gamma Release Assay (IGRA) Positive | Allogeneic Hematopoietic Cell Transplantation With Pegylated Interferon Alfa-2a for Primary and Secondary Myelofibrosis (ATIOM) [READ MORE]

Photo of Yingcheng Wu
Member Highlights

Member Highlight: Yingcheng Wu, Fu Ching Yen Scholar M.D. and Ph.D. Candidate at Fudan University

My research focuses on immune metabolism and cancer microenvironment, and as a surgeon-scientist in training, I am deeply interested in improving the outcomes of liver cancer patients. Regarding my hobbies, I really like swimming. Lastly, the best advice I’ve received is that life is an experience. This simple yet profound [READ MORE]

Clinical Trials, contributed by Howard A. Young
Clinical Trials

Clinical Trials for the week of August 21

Blocking TNF to Potentiate the ICI-dependent Immune Awakening in Melanoma (ATPIC) | Effectiveness of Zidovudine vs. Zidovudine Plus Alpha Interferon vs. Interferon for Treatment of HIV | Safety and Efficacy of Interferon-Gamma 1b in Patients With Candidemia [READ MORE]

Dr. Julie Stockis, Dr. Julia Moreno-Vicente, Dr. Thomas Yip, and Dr. Tim Halim
Special Article of Interest

Cross-talk between ILC2 and Gata3high Tregs locally constrains adaptive type 2 immunity

Regulatory T cells (Tregs) are essential for resolving inflammation and maintaining immune homeostasis. How Tregs are locally regulated in inflamed niches is poorly understood, although their expression of CD4 helper T (Th) cell lineage-defining transcription factors (i.e. Gata3, Rorγt, and Tbet) tailors their regulatory function towards a specific type of [READ MORE]