COVID-19 special collection

PMID: 34912108

The state of complement in COVID-19.

Afzali B, Noris M, Lambrecht BN, Kemper C.

Nat Rev Immunol. 2022 Feb;22(2):77-84. doi: 10.1038/s41577-021-00665-1. Epub 2021 Dec 15.PMID: 34912108 Free PMC article. Review.

PMID: 34873279

The germinal centre B cell response to SARS-CoV-2.

Laidlaw BJ, Ellebedy AH.

Nat Rev Immunol. 2022 Jan;22(1):7-18. doi: 10.1038/s41577-021-00657-1. Epub 2021 Dec 6.PMID: 34873279 Free PMC article. Review.

PMID: 34837062

Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses – are we our own worst enemy?

Wong LR, Perlman S.

Nat Rev Immunol. 2022 Jan;22(1):47-56. doi: 10.1038/s41577-021-00656-2. Epub 2021 Nov 26.PMID: 34837062 Free PMC article. Review.

PMID: 35105981

Innate immunity: the first line of defense against SARS-CoV-2.

Diamond MS, Kanneganti TD.

Nat Immunol. 2022 Feb;23(2):165-176. doi: 10.1038/s41590-021-01091-0. Epub 2022 Feb 1.PMID: 35105981 Review.

PMID: 35105983

Immunology of SARS-CoV-2 infection in children.

Chou J, Thomas PG, Randolph AG.

Nat Immunol. 2022 Feb;23(2):177-185. doi: 10.1038/s41590-021-01123-9. Epub 2022 Feb 1.PMID: 35105983 Review.

PMID: 35093190

SARS-CoV-2 infections in children: Understanding diverse outcomes.

Brodin P.

Immunity. 2022 Feb 8;55(2):201-209. doi: 10.1016/j.immuni.2022.01.014. Epub 2022 Jan 20.PMID: 35093190 Free PMC article. Review.

PMID: 35105982

The T cell immune response against SARS-CoV-2.

Moss P.

Nat Immunol. 2022 Feb;23(2):186-193. doi: 10.1038/s41590-021-01122-w. Epub 2022 Feb 1.PMID: 35105982 Review.

PMID: 35064248

A guide to immunotherapy for COVID-19.

van de Veerdonk FL, Giamarellos-Bourboulis E, Pickkers P, Derde L, Leavis H, van Crevel R, Engel JJ, Wiersinga WJ, Vlaar APJ, Shankar-Hari M, van der Poll T, Bonten M, Angus DC, van der Meer JWM, Netea MG.

Nat Med. 2022 Jan;28(1):39-50. doi: 10.1038/s41591-021-01643-9. Epub 2022 Jan 21.PMID: 35064248 Review.

PMID: 34667307

The immunology of asymptomatic SARS-CoV-2 infection: what are the key questions?

Boyton RJ, Altmann DM.

Nat Rev Immunol. 2021 Dec;21(12):762-768. doi: 10.1038/s41577-021-00631-x. Epub 2021 Oct 19.PMID: 34667307 Free PMC article. Review.

PMID: 34746804

SARS-CoV-2, COVID-19 and the Ageing Immune System.

Bartleson JM, Radenkovic D, Covarrubias AJ, Furman D, Winer DA, Verdin E.

Nat Aging. 2021 Sep;1(9):769-782. doi: 10.1038/s43587-021-00114-7. Epub 2021 Sep 14.PMID: 34746804

PMID: 35113729

IL-6 Revisited: From Rheumatoid Arthritis to CAR T Cell Therapy and COVID-19.

Kishimoto T, Kang S.

Annu Rev Immunol. 2022 Feb 3. doi: 10.1146/annurev-immunol-101220-023458. Online ahead of print.PMID: 35113729 Review.

PMID: 33522893

COVID-19-associated cytokine storm syndrome and diagnostic principles: an old and new Issue.

Yongzhi X.

Emerg Microbes Infect. 2021 Dec;10(1):266-276. doi: 10.1080/22221751.2021.1884503.PMID: 33522893 Free PMC article. Review.

PMID: 34373622

Inflammasome activation at the crux of severe COVID-19.

Vora SM, Lieberman J, Wu H.

Nat Rev Immunol. 2021 Nov;21(11):694-703. doi: 10.1038/s41577-021-00588-x. Epub 2021 Aug 9.PMID: 34373622 Free PMC article. Review.

PMID: 34678609

Off balance: Interferons in COVID-19 lung infections.

Akamatsu MA, de Castro JT, Takano CY, Ho PL.

EBioMedicine. 2021 Nov;73:103642. doi: 10.1016/j.ebiom.2021.103642. Epub 2021 Oct 19.PMID: 34678609 Free PMC article. Review.

PMID: 33850327

Is IL-6 a key cytokine target for therapy in COVID-19?

Jones SA, Hunter CA.

Nat Rev Immunol. 2021 Jun;21(6):337-339. doi: 10.1038/s41577-021-00553-8.PMID: 33850327 Free PMC article. Review.

PMID: 33837054

IL-6 modulation for COVID-19: the right patients at the right time?

Ascierto PA, Fu B, Wei H.

J Immunother Cancer. 2021 Apr;9(4):e002285. doi: 10.1136/jitc-2020-002285.PMID: 33837054 Free PMC article. Review.

PMID: 33676592

IL-6 blockade for COVID-19: a global scientific call to arms.

Murthy S, Lee TC.

Lancet Respir Med. 2021 May;9(5):438-440. doi: 10.1016/S2213-2600(21)00127-2. Epub 2021 Mar 4.PMID: 33676592 Free PMC article. Review. No abstract available.

PMID: 33837596

Capturing Cytokines with Advanced Materials: A Potential Strategy to Tackle COVID-19 Cytokine Storm.

Meng QF, Tian R, Long H, Wu X, Lai J, Zharkova O, Wang JW, Chen X, Rao L.

Adv Mater. 2021 May;33(20):e2100012. doi: 10.1002/adma.202100012. Epub 2021 Apr 10.PMID: 33837596 Free PMC article. Review.

PMID: 34234112

The signal pathways and treatment of cytokine storm in COVID-19.

Yang L, Xie X, Tu Z, Fu J, Xu D, Zhou Y.

Signal Transduct Target Ther. 2021 Jul 7;6(1):255. doi: 10.1038/s41392-021-00679-0.PMID: 34234112 Free PMC article. Review.

PMID: 33559848

The cytokine storm and thyroid hormone changes in COVID-19.

Croce L, Gangemi D, Ancona G, Liboà F, Bendotti G, Minelli L, Chiovato L.

J Endocrinol Invest. 2021 May;44(5):891-904. doi: 10.1007/s40618-021-01506-7. Epub 2021 Feb 9.PMID: 33559848 Free PMC article. Review.

PMID: 33981314

Interleukin-6, CXCL10 and Infiltrating Macrophages in COVID-19-Related Cytokine Storm: Not One for All But All for One!

Coperchini F, Chiovato L, Rotondi M.

Front Immunol. 2021 Apr 26;12:668507. doi: 10.3389/fimmu.2021.668507. eCollection 2021.PMID: 33981314 Free PMC article. Review.

PMID: 34149697

Cytokine Overproduction and Immune System Dysregulation in alloHSCT and COVID-19 Patients.

Lange A, Lange J, Jaskuła E.

Front Immunol. 2021 Jun 2;12:658896. doi: 10.3389/fimmu.2021.658896. eCollection 2021.PMID: 34149697 Free PMC article. Review.

PMID: 33995341

Cytokine Storm: The Primary Determinant for the Pathophysiological Evolution of COVID-19 Deterioration.

Chen R, Lan Z, Ye J, Pang L, Liu Y, Wu W, Qin X, Guo Y, Zhang P.

Front Immunol. 2021 Apr 28;12:589095. doi: 10.3389/fimmu.2021.589095. eCollection 2021.PMID: 33995341 Free PMC article. Review.

PMID: 34220807

COVID-19 Severity in Obesity: Leptin and Inflammatory Cytokine Interplay in the Link Between High Morbidity and Mortality.

Maurya R, Sebastian P, Namdeo M, Devender M, Gertler A.

Front Immunol. 2021 Jun 18;12:649359. doi: 10.3389/fimmu.2021.649359. eCollection 2021.PMID: 34220807 Free PMC article. Review.

PMID: 33573850

The cytokine storm in COVID-19: Further advances in our understanding the role of specific chemokines involved.

Coperchini F, Chiovato L, Ricci G, Croce L, Magri F, Rotondi M.

Cytokine Growth Factor Rev. 2021 Apr;58:82-91. doi: 10.1016/j.cytogfr.2020.12.005. Epub 2021 Jan 8.PMID: 33573850 Free PMC article. Review.

PMID: 33563543

Interferons and other cytokines, genetics and beyond in COVID-19 and autoimmunity.

Opdenakker G, Van Damme J.

Cytokine Growth Factor Rev. 2021 Apr;58:134-140. doi: 10.1016/j.cytogfr.2021.01.004. Epub 2021 Jan 29.PMID: 33563543 Free PMC article. Review.

PMID: 33071044

Type I IFN-dependent antibody response at the basis of sex dimorphism in the outcome of COVID-19.

Gabriele L, Fragale A, Romagnoli G, Parlato S, Lapenta C, Santini SM, Ozato K, Capone I.

Cytokine Growth Factor Rev. 2021 Apr;58:66-74. doi: 10.1016/j.cytogfr.2020.10.001. Epub 2020 Oct 8.PMID: 33071044 Free PMC article. Review.

PMID: 34183243

The NLRP3 inflammasome and COVID-19: Activation, pathogenesis and therapeutic strategies.

Zhao N, Di B, Xu LL.

Cytokine Growth Factor Rev. 2021 Jun 18:S1359-6101(21)00054-X. doi: 10.1016/j.cytogfr.2021.06.002. Online ahead of print.PMID: 34183243 Free PMC article. Review.

PMID: 33926774

Perspectives on anti-IL-1 inhibitors as potential therapeutic interventions for severe COVID-19.

Geng J, Wang F, Huang Z, Chen X, Wang Y.

Cytokine. 2021 Jul;143:155544. doi: 10.1016/j.cyto.2021.155544. Epub 2021 Apr 17.PMID: 33926774 Free PMC article. Review.

PMID: 33075298

Cytokine elevation in severe and critical COVID-19: a rapid systematic review, meta-analysis, and comparison with other inflammatory syndromes.

Leisman DE, Ronner L, Pinotti R, Taylor MD, Sinha P, Calfee CS, Hirayama AV, Mastroiani F, Turtle CJ, Harhay MO, Legrand M, Deutschman CS.

Lancet Respir Med. 2020 Dec;8(12):1233-1244. doi: 10.1016/S2213-2600(20)30404-5. Epub 2020 Oct 16.PMID: 33075298 Free PMC article.

PMID: 33264547

Cytokine Storm.

Fajgenbaum DC, June CH.

N Engl J Med. 2020 Dec 3;383(23):2255-2273. doi: 10.1056/NEJMra2026131.PMID: 33264547 

Free PMC article. Review. No abstract available.

PMID: 32425294

Weathering the COVID-19 storm: Lessons from hematologic cytokine syndromes.

England JT, Abdulla A, Biggs CM, Lee AYY, Hay KA, Hoiland RL, Wellington CL, Sekhon M, Jamal S, Shojania K, Chen LYC.

Blood Rev. 2021 Jan;45:100707. doi: 10.1016/j.blre.2020.100707. Epub 2020 May 15.PMID: 32425294 Free PMC article. Review.

Preliminary predictive criteria for COVID-19 cytokine storm.

Caricchio R, Gallucci M, Dass C, Zhang X, Gallucci S, Fleece D, Bromberg M, Criner GJ; Temple University COVID-19 Research Group.

Ann Rheum Dis. 2021 Jan;80(1):88-95. doi: 10.1136/annrheumdis-2020-218323. Epub 2020 Sep 25.PMID: 32978237 Review.

PMID: 32896310

The role of IL-6 and other mediators in the cytokine storm associated with SARS-CoV-2 infection.

Copaescu A, Smibert O, Gibson A, Phillips EJ, Trubiano JA.

J Allergy Clin Immunol. 2020 Sep;146(3):518-534.e1. doi: 10.1016/j.jaci.2020.07.001.PMID: 32896310 Free PMC article. Review.

PMID: 33007328

Highways to hell: Mechanism-based management of cytokine storm syndromes.

Canna SW, Cron RQ.

J Allergy Clin Immunol. 2020 Nov;146(5):949-959. doi: 10.1016/j.jaci.2020.09.016. Epub 2020 Sep 29.PMID: 33007328 Free PMC article. Review.

PMID: 33214057

A Potential Role of Interleukin 10 in COVID-19 Pathogenesis.

Lu L, Zhang H, Dauphars DJ, He YW.

Trends Immunol. 2021 Jan;42(1):3-5. doi: 10.1016/ Epub 2020 Nov 2.PMID: 33214057 Free PMC article. Review.

PMID: 33153908

Coronaviruses: Innate Immunity, Inflammasome Activation, Inflammatory Cell Death, and Cytokines.

Lee S, Channappanavar R, Kanneganti TD.

Trends Immunol. 2020 Dec;41(12):1083-1099. doi: 10.1016/ Epub 2020 Oct 15.PMID: 33153908 Free PMC article. Review.

PMID: 33051104

A Cytokine Circus with a Viral Ringleader: SARS-CoV-2-Associated Cytokine Storm Syndromes.

Cabler SS, French AR, Orvedahl A.

Trends Mol Med. 2020 Dec;26(12):1078-1085. doi: 10.1016/j.molmed.2020.09.012. Epub 2020 Sep 30.PMID: 33051104 Free PMC article. Review.

PMID: 33391477

Immunopathogenesis and treatment of cytokine storm in COVID-19.

Kim JS, Lee JY, Yang JW, Lee KH, Effenberger M, Szpirt W, Kronbichler A, Shin JI.

Theranostics. 2021 Jan 1;11(1):316-329. doi: 10.7150/thno.49713. eCollection 2021.PMID: 33391477 Free PMC article. Review.

PMID: 32929876

The Longitudinal Immune Response to Coronavirus Disease 2019: Chasing the Cytokine Storm.

Chau AS, Weber AG, Maria NI, Narain S, Liu A, Hajizadeh N, Malhotra P, Bloom O, Marder G, Kaplan B.

Arthritis Rheumatol. 2021 Jan;73(1):23-35. doi: 10.1002/art.41526. Epub 2020 Dec 1.PMID: 32929876 Review.

PMID: 32291137

Can we use interleukin-6 (IL-6) blockade for coronavirus disease 2019 (COVID-19)-induced cytokine release syndrome (CRS)?

Liu B, Li M, Zhou Z, Guan X, Xiang Y.

J Autoimmun. 2020 Jul;111:102452. doi: 10.1016/j.jaut.2020.102452. Epub 2020 Apr 10.PMID: 32291137 Free PMC article. Review.

PMID: 32961074

Cytokine storm and COVID-19: a chronicle of pro-inflammatory cytokines.

Fara A, Mitrev Z, Rosalia RA, Assas BM.

Open Biol. 2020 Sep;10(9):200160. doi: 10.1098/rsob.200160. Epub 2020 Sep 23.PMID: 32961074 Free PMC article. Review.

PMID: 33072097

COVID-19: In the Eye of the Cytokine Storm.

de la Rica R, Borges M, Gonzalez-Freire M.

Front Immunol. 2020 Sep 24;11:558898. doi: 10.3389/fimmu.2020.558898. eCollection 2020.PMID: 33072097 Free PMC article. Review.

PMID: 33621130

Perspectives on Targeting IL-6 as a Potential Therapeutic Strategy for COVID-19.

Khaedir Y, Kartika R.

J Interferon Cytokine Res. 2021 Feb;41(2):37-43. doi: 10.1089/jir.2020.0135.PMID: 33621130 Review.

PMID: 33113222

T cell immunobiology and cytokine storm of COVID-19.

Luo XH, Zhu Y, Mao J, Du RC.

Scand J Immunol. 2021 Mar;93(3):e12989. doi: 10.1111/sji.12989. Epub 2020 Nov 25.PMID: 33113222 Free PMC article. Review.

PMID: 32794180

IL-18 and infections: Is there a role for targeted therapies?

Vecchié A, Bonaventura A, Toldo S, Dagna L, Dinarello CA, Abbate A.

J Cell Physiol. 2021 Mar;236(3):1638-1657. doi: 10.1002/jcp.30008. Epub 2020 Aug 13.PMID: 32794180 Review.

PMID: 33850327 

Is IL-6 a key cytokine target for therapy in COVID-19?

Jones SA, Hunter CA. Nat Rev Immunol. 2021 Apr 13:1-3. doi: 10.1038/s41577-021-00553-8. Online ahead of print.

Bronze Sponsor of Cytokines 2021 Hybrid Meeting