Photo of Article Co-Authors Viejo-Borbolla, Jacobson, and Plückebaum
Special Article of Interest

Discovery of the first IFN-binding protein in herpes viruses reported

Viral modulation of type II interferon increases T cell adhesion and virus spread Herpes and poxviruses express viroceptors, viral proteins that bind cytokines and modulate their activity. Until now, all known viroceptors that bind interferon (IFN) have been discovered exclusively in poxviruses and inhibit IFN activity through blocking the cytokine-receptor [READ MORE]