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Biweekly newsletter of the International Cytokine & Interferon Society

Biweekly newsletter of the International Cytokine & Interferon Society

Signals+ Editors: Daniella Schwartz & Di Yu (Editors in Chief), Saurabh Chattopadhyay, Zhian Chen, Mohamed Saad & Maialen Sebastian-delaCruz

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Home#MemberHighlight

#MemberHighlight

Rosa Nguyen in her lab
Member Highlights

Member Highlight Interview: Rosa Nguyen

November 18, 2024

My lab focuses on the development of novel immunotherapies for pediatric solid tumors. We take the most promising discoveries and translate them into the clinic. [READ MORE]

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Clinical Trials, contributed by Howard A. Young
Clinical Trials

Interferon-gamma as Adjunctive Therapy in Chronic Pulmonary Aspergillosis: a Randomised Feasibility Study (INCAS)

June 1, 2025

ClinicalTrials.gov ID NCT05653193 Sponsor Manchester University NHS Foundation Trust Information provided by Manchester University NHS Foundation Trust (Responsible Party) Brief Summary This study explores the role of treatment with interferon-gamma to improve outcomes in chronic pulmonary aspergillosis (CPA). CPA is a progressive infection caused by the fungus Aspergillus affecting patients [READ MORE]

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Clinical Trials, contributed by Howard A. Young
Clinical Trials

Interferon-α for TP53 Myeloid Malignancy Post Allo-HSCT

June 1, 2025

ClinicalTrials.gov ID NCT06130579 Sponsor Peking University People’s Hospital Information provided by Xiao-Jun Huang, Peking University People’s Hospital (Responsible Party) Brief Summary To investigate the efficacy of interferon-α prophylaxis in patients with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) with TP53 mutation who were negative for minimal residual disease (MRD) [READ MORE]

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Clinical Trials, contributed by Howard A. Young
Clinical Trials

Interferon Pathway Activation in Monogenic and Nonmonogenic Forms of Pediatric SLE

June 1, 2025

ClinicalTrials.gov ID NCT06586710 Sponsor Meyer Children’s Hospital IRCCS Information provided by Carmela Errichiello, Meyer Children’s Hospital IRCCS (Responsible Party) Brief Summary Pediatric SLE includes monogenic forms, some of which involve the interferon type I (IFN-I) pathway. The IFN-I pathway is renally active in adult SLE and correlates with the extent [READ MORE]

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Young man in a market
Member Highlights

Member Highlight: Meet Kenta Yamamoto

May 19, 2025

I’m an MD/PhD student at the University of Pittsburgh Medical Scientist Training Program, in the laboratory of Dr. Sarah Gaffen, and I’m studying the functions of RNA-binding proteins in T cells mediating inflammatory disease. Previously, I studied spinal cord regeneration in the axolotl salamander with Dr Karen Echeverri and how [READ MORE]

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Photo of Dominic Ritacco
New Member Mini-Bios

Dominic Ritacco, Columbia University Medical Center

May 19, 2025

Dominic Ritacco is a graduate student in the Gaudet lab at Columbia University’s Department of Microbiology and Immunology. Dominic received his B.S. in Biochemistry from the University of Wisconsin-Madison. He has previously conducted infectious disease research in the Moormann lab at the University of Massachusetts Chan Medical School and cell [READ MORE]

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