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Featured Article!

A Year of Connection, Discovery, and Community: Celebrating 2025

As we close out 2025, we find ourselves reflecting on a year that has been nothing short of extraordinary for our global cytokine community. From groundbreaking scientific achievements to meaningful connections forged across continents, this year has reminded us why we do what we do—and why this community matters so [READ MORE]

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Society News

Year-End Giving: Support the Next Generation of Scientific Discovery

This holiday season, invest in your scientific family by supporting the Cytokine Society’s travel grant funds. Your year-end gift empowers early-career researchers to present their work, forge career-shaping connections, and advance our field together. As the year winds down and the spirit of generosity fills the air, many of us [READ MORE]

Valeriya Smaliya discovering oysters
Member Highlights

Meet Valeriya Smaliy: Uncovering GAPLINC’s Role in Macrophage Inflammation

Valeriya Smaliy is a fourth-year PhD student at UCSC studying how the long non-coding RNA GAPLINC regulates inflammation in macrophages. Her recent work identified MCCC1 as a binding partner, revealing unexpected connections between GAPLINC and mitochondrial metabolism. Beyond the lab, she’s spontaneous, discovering a love for oysters, and finding wisdom [READ MORE]

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Featured Article!

New President’s Message: A Quarter-Century Journey with The Cytokine Society

As I write this first contribution to Signals as President of THE CYTOKINE SOCIETY, I find myself thinking about my 25 years of involvement with this organization. What a long, strange trip it has been from my first Cytokine meeting in Amsterdam in 2000, a joint meeting of our parent [READ MORE]

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Member Highlights

Meet Dominic Ritacco: Exploring Cellular Self-Defense Against Chagas Disease

I am a fourth-year Ph.D. candidate in the Gaudet Lab at Columbia University. My research revolves around the idea that non-immune cells can protect themselves against pathogens through effector interferon-stimulated genes (ISGs). Many of these ISGs are poorly characterized, and I am exploring the role of these genes in Chagas [READ MORE]

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Clinical Trials

IL-1 Inhibition in Early TNBC (OZM-034)

ClinicalTrials.gov ID NCT06710197 Sponsor University Health Network, Toronto Information provided by University Health Network, Toronto (Responsible Party) Last Update Posted 2025-03-11 Study Overview Brief Summary This study will examine changes in the tumor microenvironment (TME) induced by 14 days of pre-operative IL-1-inhibiting therapy among patients with early breast cancer (including [READ MORE]

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Clinical Trials

Biological, Prospective Study Evaluating the Dosage of Plasma Cytokines Including the FLT3 Ligand and IL6 of Patients Treated With Non-intensive Chemotherapy (CYTOK-AZA)

ClinicalTrials.gov ID NCT06439199 Sponsor Nantes University Hospital Information provided by Nantes University Hospital (Responsible Party) Last Update Posted 2024-09-27 Study Overview Brief Summary There are 2 possible treatments for the treatment of Acute Myelogenous Leukemia (AML), high-risk myelodysplastic syndromes (HR-MDS) or chronic myelomonocytic leukemia (CMML): intensive curative chemotherapy , and [READ MORE]

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Clinical Trials

The Effect of Intrathecal Morphine and Erector Spina Plan Block on Serum Cytokine Levels and Chronic Pain in Caesarean Section Surgery

ClinicalTrials.gov ID NCT06684015 Sponsor Ankara University Information provided by Fatih Kurt, Ankara University (Responsible Party) Last Update Posted 2024-11-12 Study Overview Brief Summary Working Title The Effect of Intrathecal Morphine and Erector Spina Plan Block on Serum Cytokine Levels and Chronic Pain in Caesarean Section Surgery Study Description This study [READ MORE]

Annual Meeting

Cytokines 2025 Rocks Seattle, Nite Wave Style!

The Pacific Northwest showed us how it’s done! From November 2-5, 2025, the Westin Seattle welcomed 535 cytokine researchers from 20 countries for what can only be described as an electrifying convergence of cutting-edge science, authentic community, and yes—some seriously good 80’s cover music. A Meeting That Hits All the [READ MORE]

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Member Highlights

Meet Mohammad Arifuzzaman: Decoding How Diet and Microbiota Shape Inflammation

I’m an Assistant Professor of Immunology in the Department of Medicine at Weill Cornell Medicine in New York City, and our research focuses on understanding nutritional regulation of inflammation. We aim to determine how diet and gut microbiota regulate inflammatory cytokines in the intestine and distant tissue sites. Out of [READ MORE]