Graphical abstract and citation of recent article from lab of Dr. Edward Chuong
Special Article of Interest

“Regulation of human interferon signaling by transposon exonization” published in Cell

The following interview was conducted by Signals+ Editor Maialen Sebastian-delaCruz, Ph.D. Connect with her on LinkedIn. A recent study by Pasquesi et al from the Chuong lab published in Cell, “Regulation of human interferon signaling by transposon exonization” showed that transposable element exonization can yield functional protein isoforms as seen for [READ MORE]

Elias A. Said, Ph.D., Associate Professor, Sultan Qaboos University, Muscat, Oman
Member Highlights

Member Highlight: Meet Elias Said

The following interview was conducted by Signals+ Editor Maialen Sebastian-delaCruz, Ph.D. Connect with her on LinkedIn. I am a researcher in the Immunology field, specifically innate immunity and cytokines. Also, an Associate Editor for scientific journals. My research has led to significant achievements, such as identifying the role of PD-1 in [READ MORE]

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Clinical Trials

Single-arm, Dose-escalation Trial of Long-acting Recombinant Human IL-7 (NT-I7, Efineptakin Alfa) for Idiopathic CD4 Lymphopenia

ClinicalTrials.gov ID NCT05600920 Sponsor National Institute of Allergy and Infectious Diseases (NIAID) Information provided by National Institutes of Health Clinical Center (CC) (National Institute of Allergy and Infectious Diseases (NIAID)) Study Overview Brief Summary Background: Idiopathic CD4 lymphopenia (ICL) is a syndrome characterized by low levels of certain immune cells [READ MORE]

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Clinical Trials

Serum IL 26 as a Marker of Disease Activity in SLE

ClinicalTrials.gov ID NCT05161988 Sponsor: Assiut University Information provided by Fatma alzahraa Mustafa Abdelbary Thabet, Assiut University (Responsible Party) Study Overview Brief Summary Assessment of serum Interleukin 26 level in SLE patients and compare it with healthy controls. Association of serum interleukin 26 with SLE activity and severity. Detailed Description Systemic [READ MORE]

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Clinical Trials

Cancer Ratio,Pleural Fluid Adenosine Deaminase,Lactate Dehydrogenase, interferonY, Tumor Necrosis Factor,and Interleukins{2,12,18}for Differentiation Between Malignant and Non Malignant Pleural Effusion

ClinicalTrials.gov ID NCT05693727 Sponsor: Assiut University Information provided by Mona Adel, Assiut University (Responsible Party) Study Overview Brief Summary To evaluate the ability of cancer ratio and pleural fluid markers to discriminate between malignant and non malignant effusion Detailed Description Pleural effusion is a common clinical entity affecting approximately 1.5 [READ MORE]

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Members in the News

Share Your Recent Publication or Interesting Project

The Signals+ Editors want to hear from YOU! Everyone enjoys reading about what colleagues are doing. If you have an interesting study or recent publication you’d like showcased in Signals+, please take a moment to submit it here.*  Thank you for being an essential part of our community, and we look [READ MORE]