[68Ga]Ga-Sa-DABI-4 PET Imaging of Stimulator of Interferon Gene Expression in Cancer Patients

ClinicalTrials.gov ID NCT06419361
Sponsor First Affiliated Hospital of Chongqing Medical University
Information provided by Xiaoyang Zhang, First Affiliated Hospital of Chongqing Medical University (Responsible Party)
Last Update Posted 2025-06-04

Brief Summary

Stimulator of interferon gene (STING) protein plays a vital role in the immune surveillance of tumor microenvironment. Monitoring STING expression in tumors benefits the relevant STING therapy. This study will investigate the safety, biodistribution and potential usefulness of a novel 68Ga-labeled agonist ([68Ga]Ga-Sa-DABI-4) for noninvasive positron emission tomography (PET) imaging of STING expression in the tumor microenvironment.