Headshot of Maria M Caffarel, PhD
New Member Mini-Bios

Silencing the Signals That Spread Cancer: Meet New Member María Muñoz Caffarel, Ph.D.

Dr. María M Caffarel is an Ikerbasque Researcher at the Biogipuzkoa Health Research Institute (formerly known as Biodonostia) in San Sebastian (Spain) where she leads the Breast Cancer group within the Oncology Area. Her team’s main focus is the study of the molecular mechanisms involved in breast cancer progression, with [READ MORE]

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Other News of Interest

From Lockdown to Global Dialogue: How MycoTalks and MycoClinics Grew a Virtual Fungal Community

When laboratories closed and conferences were cancelled during the early months of the COVID19 pandemic, the scientific world abruptly lost the informal conversations and seminar exchanges that fuel collaboration and new ideas. To mitigate these effects in the fungal research community, a small group of researchers created an online seminar [READ MORE]

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Clinical Trials

Evaluate the Efficacy and Safety of Interferon-α Combined With ATO in the Treatment of Arsenic-resistant APL (APL)

Evaluate the Efficacy and Safety of Interferon-α Combined With ATO in the Treatment of Arsenic-resistant APL (APL) ClinicalTrials.gov ID NCT06450145 Sponsor Zhejiang Provincial People’s Hospital Information provided by Zhejiang Provincial People’s Hospital (Responsible Party Brief Summary This study was a single-arm, open study. After the screening period, arsenic-resistant APL patients [READ MORE]

Clinical Trials

Interferon-α for TP53 Myeloid Malignancy Post Allo-HSCT

Interferon-α for TP53 Myeloid Malignancy Post Allo-HSCT ClinicalTrials.gov ID NCT06130579 Sponsor Peking University People’s Hospital Information provided by Xiao-Jun Huang, Peking University People’s Hospital (Responsible Party) Last Update Posted 2025-06-03 Brief Summary To investigate the efficacy of interferon-α prophylaxis in patients with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) [READ MORE]

Clinical Trials

Interferon-gamma as Adjunctive Therapy in Chronic Pulmonary Aspergillosis: a Randomised Feasibility Study (INCAS)

Interferon-gamma as Adjunctive Therapy in Chronic Pulmonary Aspergillosis: a Randomised Feasibility Study (INCAS) ClinicalTrials.gov ID NCT05653193 Sponsor Manchester University NHS Foundation Trust Information provided by Manchester University NHS Foundation Trust (Responsible Party) Last Update Posted 2025-03-03 Brief Summary This study explores the role of treatment with interferon-gamma to improve outcomes [READ MORE]

Members in the News

New Checkpoint in TLR7/8 Sensing Rewrites Innate Immune Rules

A recent study by Alharbi et.al. from the Gantier Lab published in Nature Immunology, “2′-O-Methyl-guanosine RNA fragments antagonize TLR7 and TLR8 to limit autoimmunity”, showed that TLR7 and TLR8 sensing is kept in check by naturally occurring 2′-O-methyl (2′-OMe)-modified ribosomal RNA fragments, avoiding autoimmune responses to host RNA in the [READ MORE]

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Member Highlights

Meet Jason Weinstein: Decoding the Dialogue Between T and B Cells

I am an associate professor at Rutgers University in New Jersey, and I’m on a mission to decode the conversation between CD4+ T cells and B cells. These T cells use cytokines as their messages, and I am particularly fascinated by the cytokines secreted by a subset of these T [READ MORE]

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In Memoriam

In Memoriam: Remembering Dr. Andrew C. Larner (1952–2025)

On November 23, 2025, the field of interferon signaling lost one of its luminary scientists, Dr. Andrew C. Larner. Andy, as many of us knew him, was Professor Emeritus of Biochemistry and Molecular Biology at Virginia Commonwealth University and a long-standing member of the Cytokine Society (formerly ISICR and ICIS). [READ MORE]

Photo Credit: Burcu Elmas (pexels.com 10051526)
Reviews of Interest

Reviews of Interest Curated by Dr. Zhian (Anthony) Chen

Dr. Zhian (Anthony) Chen has compiled the following review articles of relevance to researchers in the field of cytokine, chemokine and interferon biology. Dr. Chen is a Senior Research Fellow and Group Leader at the University of Queensland Frazer Institute. They lead a team under the UQ Health Research Accelerator [READ MORE]

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President's Letter

Going for Gold: The Olympic Spirit of Cytokine Science

The Winter Olympics brought a much-needed mental break during a February- the middle of Northwestern’s Winter Quarter, a respite from undergraduate teaching, grant writing, and the pandemonium of ongoing political noise. The beauty of the snowy Milan-Cortino mountains of was a perfect backdrop to the gathering of outstanding athletes from [READ MORE]