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Clinical Trials

Effect of IL17 Inhibitor in Comparison With Anti-TNF in Patients With Ankylosing Spondylitis

ClinicalTrials.gov ID NCT06642207 Sponsor Sohag University Information provided by Manar Gamal Abdelfattah, Sohag University (Responsible Party) Last Update Posted 2024-10-30 Brief Summary Ankylosing spondylitis (AS) is a chronic, inflammatory autoimmune disease characterized by axial bone inflammation. The main clinical manifestations include back pain and progressive spinal rigidity, as well as [READ MORE]

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Clinical Trials

The Effects of IL-1 Blockade on Inotrope Sensitivity in Patients With Heart Failure (AID-HEART)

ClinicalTrials.gov ID NCT06062966 Sponsor Virginia Commonwealth University Information provided by Virginia Commonwealth University (Responsible Party) Last Update Posted 2025-04-27 Brief Summary End-stage heart failure (HF) is a progressive illness with a mortality rate similar to most advanced cancers.Roughly 5% of patients with HF have end-stage disease that is refractory to [READ MORE]

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Clinical Trials

IL-1 Inhibition in Early TNBC (OZM-034)

ClinicalTrials.gov ID NCT06710197 Sponsor University Health Network, Toronto Information provided by University Health Network, Toronto (Responsible Party) Last Update Posted 2025-03-11 Study Overview Brief Summary This study will examine changes in the tumor microenvironment (TME) induced by 14 days of pre-operative IL-1-inhibiting therapy among patients with early breast cancer (including [READ MORE]

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Clinical Trials

Biological, Prospective Study Evaluating the Dosage of Plasma Cytokines Including the FLT3 Ligand and IL6 of Patients Treated With Non-intensive Chemotherapy (CYTOK-AZA)

ClinicalTrials.gov ID NCT06439199 Sponsor Nantes University Hospital Information provided by Nantes University Hospital (Responsible Party) Last Update Posted 2024-09-27 Study Overview Brief Summary There are 2 possible treatments for the treatment of Acute Myelogenous Leukemia (AML), high-risk myelodysplastic syndromes (HR-MDS) or chronic myelomonocytic leukemia (CMML): intensive curative chemotherapy , and [READ MORE]

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Clinical Trials

The Effect of Intrathecal Morphine and Erector Spina Plan Block on Serum Cytokine Levels and Chronic Pain in Caesarean Section Surgery

ClinicalTrials.gov ID NCT06684015 Sponsor Ankara University Information provided by Fatih Kurt, Ankara University (Responsible Party) Last Update Posted 2024-11-12 Study Overview Brief Summary Working Title The Effect of Intrathecal Morphine and Erector Spina Plan Block on Serum Cytokine Levels and Chronic Pain in Caesarean Section Surgery Study Description This study [READ MORE]

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Clinical Trials

A Study of 19-28z/IL-18 in People With Acute Lymphoblastic Leukemia (ALL)

ClinicalTrials.gov ID NCT06287528 Sponsor Memorial Sloan Kettering Cancer Center Information provided by Memorial Sloan Kettering Cancer Center (Responsible Party) Last Update Posted 2025-05-21 Study Overview Brief Summary Participants will have a sample of their white blood cells, called T cells, collected using a procedure called leukapheresis. The collected T cells [READ MORE]

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Clinical Trials

Intraperitoneal Cytokine-Induced Memory Like (CIML) Natural Killer (NK) Cells in Recurrent Ovarian Cancer

ClinicalTrials.gov ID NCT06321484 Sponsor Dana-Farber Cancer Institute Information provided by Rebecca Porter, MD, PhD, Dana-Farber Cancer Institute (Responsible Party) Last Update Posted 2024-11-01 Study Overview Brief Summary The goal of this research study is to evaluate the safety and effectiveness of the use of cytokine-induced memory-like (CIML) natural killer (NK) [READ MORE]

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Clinical Trials

Effect of Quranic Recitation and Classical Music on Pain Intensity and Interleukin-6 Levels After Lower Limb Orthopedic Surgery with Intrathecal Anesthesia (QRCM)

ClinicalTrials.gov ID NCT06713044 Sponsor Universitas Jenderal Soedirman Information provided by Guruh Perkasa, Universitas Jenderal Soedirman (Responsible Party) Last Update Posted 2024-12-03 Study Overview Brief Summary The goal of this study is to determine the effect of murottal and classical music on postoperative pain intensity and interleukin 6 levels in patients [READ MORE]

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Clinical Trials

Clinical Trial of IL – 22BP Safety, Tolerability, and Antitumor Activity in Refractory Solid Tumors.

ClinicalTrials.gov ID NCT07040943 Sponsor West China Hospital Information provided by Xingchen Peng, West China Hospital (Responsible Party) Last Update Posted 2025-07-01 Brief Summary This study aims to investigate the safety and efficacy of the IL-22BP in patients with refractory malignant solid tumors. Detailed Description Cancer is a leading global cause [READ MORE]

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Clinical Trials

Effectiveness and Safety of Zingiber Officinale Transdermal Patch for Acne Vulgaris; Study of Interleukin 1 and Skin Microbiome

ClinicalTrials.gov ID NCT06787222 Sponsor Hasanuddin University Information provided by Rini Amanda Carolina Saragih, Hasanuddin University (Responsible Party) Last Update Posted 2025-01-27 Brief Summary The goal of this clinical trial is to investigate the effectivity and safety of mild to moderate acne vulgaris therapy using Zingiber officinale 5 % transdermal patch. [READ MORE]