At each Annual Scientific Meeting there shall be an Annual Business Meeting of the Membership of the Society, presided over by the President. Five percent of the Members shall constitute a quorum. This is the presentation of the 2021 Annual Business Meeting of the International Cytokine & Interferon Society which was postponed when the Annual meeting was not able to take place in Cardiff and pivoted to a Virtual Meeting. We invite members of the ICIS as well as others interested in cytokine biology, to view the presentation. Members can leave comments for ICIS Leadership using the form on the webpage.