2025 - Biweekly newsletter of The Cytokine Society

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An mRNA-based broad-spectrum antiviral inspired by ISG15 deficiency protects against viral infections in vitro and in vivo

September 14, 2025

A recent study, “An mRNA-based broad-spectrum antiviral inspired by ISG15 deficiency protects against viral infections in vitro and in vivo,” by Yemsratch Akalu, Roosheel S. Patel, Justin Taft, Rodrigo Canas-Arranz et. al., and published in Science Translational Medicine identified 10 ISGs – out of thousands of antiviral host genes – [READ MORE]

Member Highlights

Prof. Burkhard Becher – From Razor Analogies to Cytokine Paradoxes

September 14, 2025

I’m a Professor at the Institute of Experimental Immunology at the University of Zurich in Switzerland, and what is my research about? Cytokines, of course! Our teams research focuses on cytokine networks and their roles in immune regulation, chronic inflammation, and cancer. Regarding ICIS, I have been a member for [READ MORE]

ICIS President and President-Elect, Sarah Gaffen and Curt Horvath in front of Gang Nam hands, Seoul, Korea

Welcome to Cytokines2025 in Seattle

August 30, 2025

By Sarah Gaffen and Curt Horvath Drs. Gaffen and Horvath are the President and President-Elect of the Cytokine Society September 3, 2025 IT’S ALMOST HERE, CYTOKINES2025! As the summer winds down and the academic year approaches, THE Cytokine event of the year is rapidly approaching. So much has happened to [READ MORE]

Behind the Scenes: The Making of Cytokines 2025

August 30, 2025

As you pick up your badge and settle into that first session, everything appears to run like clockwork. The venue is perfectly appointed, the speakers are ready, the technology works seamlessly, and the coffee is hot. What you might not realize is the intricate orchestration that began more than a [READ MORE]

Member Highlights

Member Spotlight: Achille Broggi Explores Gut Immunity

August 30, 2025

I currently work at the Center for Immunology Marseille Luminy (CIML) in Marseille, France where I lead the team “Innate immunity at mucosal sites”. In our team we are interested in understanding innate immune responses in the intestine, and in particular how immune cells, epithelial cells and microbes communicate during [READ MORE]

Clinical Trial of IL – 22BP Safety, Tolerability, and Antitumor Activity in Refractory Solid Tumors.

August 30, 2025

ClinicalTrials.gov ID NCT07040943 Sponsor West China Hospital Information provided by Xingchen Peng, West China Hospital (Responsible Party) Last Update Posted 2025-07-01 Brief Summary This study aims to investigate the safety and efficacy of the IL-22BP in patients with refractory malignant solid tumors. Detailed Description Cancer is a leading global cause [READ MORE]

Effectiveness and Safety of Zingiber Officinale Transdermal Patch for Acne Vulgaris; Study of Interleukin 1 and Skin Microbiome

August 30, 2025

ClinicalTrials.gov ID NCT06787222 Sponsor Hasanuddin University Information provided by Rini Amanda Carolina Saragih, Hasanuddin University (Responsible Party) Last Update Posted 2025-01-27 Brief Summary The goal of this clinical trial is to investigate the effectivity and safety of mild to moderate acne vulgaris therapy using Zingiber officinale 5 % transdermal patch. [READ MORE]

Effects of Interleukin (IL)-17A Inhibition on Idiopathic Subglottic Stenosis

August 30, 2025

ClinicalTrials.gov ID NCT05309616 Sponsor Yale University Information provided by Yale University (Responsible Party) Last Update Posted 2025-02-25 Brief Summary The purpose of this phase 2 study is to examine if inhibiting IL-17A activation using the biologic drug Taltz, in idiopathic subglottic stenosis patients will decrease scar fibroblast proliferation therefore reducing [READ MORE]

Headshots of four invited speakers - Cytokines 2025

Star-Studded Speaker Lineup Makes Cytokines 2025 a Must-Attend Event

August 17, 2025

Recent Achievements Among Cytokines 2025 Speakers demonstrate the caliber of research being presented at Cytokines 2025, spanning breakthrough discoveries in innate immunity, novel therapeutic targets, and translational research with real clinical potential. The combination of established leaders and rising stars ensures attendees will hear about the most cutting-edge developments in [READ MORE]

Cytokine Society Member Dr. Adriana Forero Receives Prestigious Burroughs Wellcome Fund PATH Award

August 17, 2025

We are delighted to congratulate Cytokine Society member Dr. Adriana Forero on receiving the highly competitive Burroughs Wellcome Fund Investigators in the Pathogenesis of Infectious Disease (PATH) Award. This prestigious $505,000 five-year award recognizes exceptional researchers with demonstrated potential to advance our understanding of infectious disease pathogenesis, with a current [READ MORE]