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Clinical Trials

Early Interferon-beta Treatment for West-Nile Virus Infection

ClinicalTrials.gov ID NCT06510426 Sponsor Tel-Aviv Sourasky Medical Center Study Overview – Brief Summary West Nile virus (WNV) is a mosquito-borne virus which in majority of cases causes only self-limited disease. Despite that, in minority of cases (~0.5%) it can infect the brain and cause severe and even life-threatening disease (neuroinvasive disease). [READ MORE]

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Clinical Trials

Safety and Efficacy of Interferon-Gamma 1b in Patients with Candidemia

ClinicalTrials.gov ID NCT04979052 Sponsor Radboud University Medical Center Study Overview – Brief Summary A multi-center open label adaptive randomized interventional phase 2 study to evaluate safety and efficacy of rIFN-y treatment in patients with candidemia. Detailed Description A multi-center open label adaptive randomized interventional phase 2 study to evaluate safety [READ MORE]

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Clinical Trials

Interferon Alpha Therapy for Cervical CINI and HPV Infection

ClinicalTrials.gov ID NCT06137950 Sponsor Mongolian National University of Medical Sciences Study Overview – Brief Summary Mongolia is a traditionally nomadic and population is scarce in rural areas. Thus, the medical care service is not sufficient. In 2000, Mongolian government has developed and implemented the millennium project in cooperation with WHO. [READ MORE]

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Clinical Trials

Recombinant Interleukin-15

Recombinant Interleukin-15 in Combination With Checkpoint Inhibitors Nivolumab and Ipilimumab in People With Refractory Cancers ClinicalTrials.gov ID NCT03388632 Sponsor National Cancer Institute (NCI) Information provided by National Institutes of Health Clinical Center (CC) (National Cancer Institute (NCI)) (Responsible Party)

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Clinical Trials

Role of IL-5R Signaling

Role of IL-5R Signaling in Non-eosinophil Upper Airway Cells in CRSwNP (RECAP-5) ClinicalTrials.gov ID NCT05672030 Sponsor Brigham and Women’s Hospital Information provided by Tanya Laidlaw, MD, Brigham and Women’s Hospital (Responsible Party)

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Clinical Trials

Single-arm, Dose-escalation Trial of Long-acting Recombinant Human IL-7 (NT-I7, Efineptakin Alfa) for Idiopathic CD4 Lymphopenia

ClinicalTrials.gov ID NCT05600920 Sponsor National Institute of Allergy and Infectious Diseases (NIAID) Information provided by National Institutes of Health Clinical Center (CC) (National Institute of Allergy and Infectious Diseases (NIAID)) Study Overview Brief Summary Background: Idiopathic CD4 lymphopenia (ICL) is a syndrome characterized by low levels of certain immune cells [READ MORE]

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Clinical Trials

Serum IL 26 as a Marker of Disease Activity in SLE

ClinicalTrials.gov ID NCT05161988 Sponsor: Assiut University Information provided by Fatma alzahraa Mustafa Abdelbary Thabet, Assiut University (Responsible Party) Study Overview Brief Summary Assessment of serum Interleukin 26 level in SLE patients and compare it with healthy controls. Association of serum interleukin 26 with SLE activity and severity. Detailed Description Systemic [READ MORE]

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Clinical Trials

Cancer Ratio,Pleural Fluid Adenosine Deaminase,Lactate Dehydrogenase, interferonY, Tumor Necrosis Factor,and Interleukins{2,12,18}for Differentiation Between Malignant and Non Malignant Pleural Effusion

ClinicalTrials.gov ID NCT05693727 Sponsor: Assiut University Information provided by Mona Adel, Assiut University (Responsible Party) Study Overview Brief Summary To evaluate the ability of cancer ratio and pleural fluid markers to discriminate between malignant and non malignant effusion Detailed Description Pleural effusion is a common clinical entity affecting approximately 1.5 [READ MORE]

Clinical Trials, contributed by Howard A. Young
Clinical Trials

Clinical Trials – updated December 18, 2024

1) Estimation of the Tissue and Serum Levels of Interleukin (IL) -35 in Mycosis Fungoides: a Case Control Study | 2) Impact of Smoking on Salivary Interleukin (IL)-39, IL-41, IL-1β, TNF-α Levels in Periodontal Disease | 3) Targeting IL-17A for Treatment-Resistant Depression [READ MORE]